Jian Zhou,* Weiqiang Ju,* Xiaopeng Yuan, Xiaofeng Zhu, Dongping Wang, Xiaoshun HeOrgan Transplant Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China *These authors contributed equally to this work: Hyperosmolar nonketotic hyperglycemic coma is a serious, rare complication induced by methylprednisolone pulse therapy for acute rejection after orthotopic liver transplantation. Herein, we report an unusual case of a 58-year-old woman who experienced acute rejection at 30 months after OLT, only one case in which HNKHC resulted in (...) MP pulse therapy for acute rejection in all 913 recipients in our center. The general morbidity of HNKHC was 1.09‰ in this study. HNKHC is characterized by rapid onset, rapid progression, and a lack of specific clinical manifestations. High-dose MP management was a clear risk factor. The principle of treatment included rapid rehydration, low-dose insulin infusion, and correcting disorders of electrolytes and acidosis. In conclusion, clinicians considering MP pulse therapy after OLT should be alert to the occurrence of HNKHC. Keywords: liver transplantation, complications, hyperosmolar nonketotic hyperglycemic coma, methylprednisolone pulse therapy, principle of treatment. (shrink)

In Early Christian Ethics in Interaction with Jewish and Greco-Roman Contexts experts from various fields analyze the process of transformation of early Christian ethics because of the ongoing interaction with Jewish, Greco-Roman and ...

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 477 (p. 32), although some might consider him to have been an important historian of logic. I am not certain that citing Carnap and Heideggar (p. 75) can do much to clarify Vires. When one reads 'Henrique Estienne' and "Hipotiposes pirronicas" (p. 266) in an Italian book he is a bit taken aback and wonders whether the author has done his homework. The writer missed a golden (...) opportunity to connect Galileo to the tradition, for his still unpublished Quaestiones on logic and the De motu (both written before 1600) have many interesting comments which tie in directly with the material developed in this volume. This could have provided an excellent bridge to the next'century, when the analytic method began to take a more central role in scientific and methodological discussions. There is still room for a number of studies on the evolution of the analytic method during the Renaissance. Unfortunately Crescini's study barely scratches the surface of this immense subject. Let us hope that his book will at least have the effect of encouraging others to treat the matter with more care, in greater depth, and more exhaustively. The volume is provided with a preface by Giorgio Radetti, who claims more for it than it actually provides, as well as noting that it is the first part of a more comprehensive study by the same author on the formation of the analytic method in Cartesian philosophy (p. 5). The book has a useful index, but unfortunately no bibliography. CHARLESB. ScxiMrrr The University of Leeds Le thomisme et la pens#e italienne de la Renaissance. By Paul Oskar Kristeller. Conference Albert-le-Grand 1965. (Montr6ah Institut d'~tudes m~di~vales, and Paris: Vrin, 1967. Pp. 287. $6) Surprisingly little is known about the later history of Thomism. This brief but very rich lecture by Professor Kristeller, renowned historian of Italian Renaissance philosophy, examines one period in the later career of St. Thomas' thought. This study, based chiefly on unpublished source material, shows that Thomas was very much present to both the humanists and to the academic philosophers during the Renaissance. Such leading humanists as Lorenzo Valla, Giovanni Pico della Mirandola, and Marsilio Ficino, quote St. Thomas frequently and with approval. Even the unfavorable attitudes of Ermolao Barbaro or Baptista Mantuanus show that Thomas was already the most celebrated of mediaeval philosophers. The professors of philosophy at Italian universities, such as Pierre Pomponazzi, speak of Thomas with great respect and regard his theology as in conformity with the truths of faith, even when they reject his philosophy as being in disaccord with the authentic teaching of Aristotle. St. Thomas made a continuous contribution to the development of Renaissance theology and philosophy. Yet the principal Italian thinkers did not follow him strictly nor fall under his exclusive influence. Thomas is merely one of the most important sources, not the prevailing influence, in Renaissance thought. Ficino, for example, is,178 HISTORY OF PHILOSOPHY in accord with Thomas on certain important points, but his own theology is more in the spirit of Plato and Augustine. Professor Kristeller's vast learning is at the service of admirably balanced conclusions. Not everyone will agree with all his interpretations; Ficino perhaps did not imagine himself to be "constructing a system of philosophy" (p. 96) since the very title of his work, Theologia platonica, suggests that he continues, with new materials, the labor of mediaeval theolo#ans. And Ficino's doctrine of the continuity of the supernatural life of the soul in this world and the next (p. 120) seems to be completely in accord with Thomas. But the author's very careful scholarly method and sound general conclusions are beyond criticism. Two hitherto unpublished Latin texts are printed in critical edition at the end of the French lecture, the Opus aureum in Thomistas by Baptists Mantuanus, which is anti-Thomas, and the Opusculum ad Laurentium Medicem on beatitude, by Vincentius Bandellus, which is pro-Thomas. Like Professor Kristeller's fine lecture, these new texts are a permanent contribution to scholarship. PAUL J. W. MILLER University of Colorado The Anatomy of Leviathan. By F. S. McNeilly. (New York: St. Martin's Press, 1968. Pp... (shrink)

Peut-être que jusqu'ici dans les recherches philosophiques sur la nature du temps on a attribué trop peu d'attention à la distinction entre « temps » comme catégorie mathématique d'une part, et « temps » comme il est réalisé dans des processus et des périodes d'autre part. Quand on essaie de combler ce vide, on éprouve le besoin d'impliquer dans ses considérations l'apparition fréquente de « nouveauté » et de « commencement ». C'est pourquoi on examine dans la première partie de (...) cet article comment nous nous formons une notion mathématique du temps. Il apparaît que cela se fait en idéalisant la perception des périodes. On s'imagine que l'unité du temps une fois choisie peut être reproduite exactement, et même jusqu'à l'inñni. En outre on s'imagine que chaque période peut être divisée en des intervalles arbitrairement petits. Un instant est pensé comme une limite nette entre le temps qui précède et le temps qui suit ; ici la séparation entre les deux parties du temps est posée comme absolue contre arrière-plan d'un temps dont justement la cohérence est posée comme absolue. C'est ainsi que naît la catégorie du temps comme une possibilité homogène, toujours égale à elle-même pour indiquer des instants indivisibles et pour délimiter des périodes, à savoir une possibilité qui s'étend sans limites des deux côtés de l'instant actuel, aussi bien vers l'avenir que vers le passé. Quand on indique un instant, deux notions contradictoires sont posées en même temps, à savoir une séparation absolue et une cohérence absolue. Dans la physique ce schéma mathématique s'avère extrêmement utile. Pourtant il s'agit de se rendre toujours compte de l'applicabilité défectueuse de ce schéma, de sorte qu'on fasse attention aux complications qui exigent un complément et une correction de la théorie. Quand on applique le même schéma aussi aux processus vitaux et aux événements psychiques, alors l'incohérence entre le schéma mathématique et la succession réelle des périodes se trouve encore plus grande. Dans la deuxième partie on analyse le « commencement ». De la manière la plus originelle un commencement se présente devant nous, quand nous essayons d'avoir une vue d'ensemble de notre propre vie, comme elle se trouve dans notre mémoire. Dans le passé nous rencontrons alors une frontière que nous ne pouvons pas marquer cependant nettement sur une échelle mathématique. Ainsi en analysant chaque commencement on doit distinguer de nouveau soigneusement le commencement dans le domaine mathématique de celui dans l'ordre réel. Le caractère abrupt qui est propre à un commencement « mathématique » se trouve absent dans un commencement « réel ». Dans la troisième partie il est démontré que le temps et le commencement sont inséparablement liés l'un à l'autre. Le temps réel apparaît partout dans des périodes ayant un commencement et ainsi dans un ensemble compliqué de commencement et de permanence. Toutes les totalités dans la nature vivante et dans la nature inanimée, les individus ainsi que les espèces, ont été neuves une fois. Avant ce commencement multiple notre univers a été neuf. Cependant, alors il appert que cette mesure perd son utilité. Lorsque l'univers était encore en gestation, notre temps, lui aussi, avec sa mesure était en formation. C'est pourquoi une localisation exacte du commencement de l'univers sur l'échelle du temps n'est pas seulement impossible, mais même absurde. Cependant, si un commencement ne peut jamais être déñni de façon mathématique, il est pourtant défini de sa manière particulière dans le temps, c'est à dire par une définition qui essentiellement contient une certaine imprécision. Quant au commencement de l'univers les sciences physiques conduisent par des chemins différents à un même résultat, et font conclure à un âge de l'univers de quatre milliards et demi d'années environ. Finalement une question concernant la notion de création se présente. La tradition connaît en effet une notion de création dans un sens très stricte, distinguée des notions de « conservatio » et de « concursus ». On a l'habitude de lier le fait de la création à un seul ou à quelques instants. Mais nous croyons pouvoir démontrer que dans la dépendance que les créatures ont a l'égard du Créateur, il y a toujours aussi un aspect d' « être créé » dans le sens cité plus haut, un aspect qui se met d'autant plus au premier rang qu'il y a plus de nouveauté et de discontinuité vis à vis du passé. (shrink)

Gibbon was a far more subtle, serious and empathetic historian of the triumph of Christianity than his reputation as a sneering infidel historian implies, or so argues Liebert in this short and wel...

Red List details the ‘Other History’ of MI5’s activities between WWI and the end of the Cold War. Not that of counter-Soviet and counter-Irish Republican espionage, but the pursuit of British intel...

ABSTRACT This article recovers the discussion of the relationship between religion, human nature and happiness in the Scottish Enlightenment physician John Gregory’s (1724–1773) A Comparative View of Human Nature (1765). Through examining Gregory’s best-selling but understudied text, this article explores how the Aberdeen Enlightenment’s own branch of the wider Scottish ‘science of human nature’, centred at the famous Aberdeen Philosophical Society, was as deeply concerned with the study of religion as it was the philosophy of mind. Gregory examined how the (...) purported cultural spread of dogmatic scepticism, associated by the Aberdonians with David Hume, threatened individual happiness and social tranquillity by removing the crutch of religious belief upon which the multitude (though not the philosopher) depended. In doing so, it suggests that the contribution made by physicians to the Scottish Enlightenment’s engagement with religion has been unjustly ignored. (shrink)

Volume 28, Issue 1, January 2020, Page 202-204.

This study argues that the English-born, Edinburgh-educated and Bath-based physician William Falconer (1744–1824) authored the only stadial history published during the British Enlightenment that analysed the influence of socio-economic context upon religious belief. A survey of the conjectural histories of religion written by the leading literati demonstrates that discussion of religion by the Scottish literati was undertaken separate from the “Scottish narrative” of stadial economic and political progress. We have to turn to Falconer’s Remarks on the Influence of Climate (1781) (...) to see a four-stage history of religion that related belief and practice to wider social and economic developments. While heavily derivative of Montesquieu’s De l’Esprit des Lois (1748), Falconer’s Remarks has some claim to theoretical innovation and used his conjectural history to tell a story of English (not British) religious exceptionalism. Moreover, the work was received as a serious contribution to the late Enlightenment’s science of human nature and society. (shrink)

A major concern of public health authorities is to also encourage adults to be exposed to enriched environments during the pandemic lockdown, as was recently the case worldwide during the COVID-19 outbreak. Games for adults that require physical activity, known as exergames, offer opportunities here. In particular, the output of the gaming industry nowadays offers computer games with extended reality which combines real and virtual environments and refers to human-machine interactions generated by computers and wearable technologies. For example, playing the (...) game in front of a computer screen while standing or walking on a force plate or treadmill allows the user to react to certain infrastructural changes and obstacles within the virtual environment. Recent developments, optimization, and minimizations in wearable technology have produced wireless headsets and sensors that allow for unrestricted whole-body movement. This makes the virtual experience more immersive and provides the opportunity for greater engagement than traditional exercise. Currently, XR serves as an umbrella term for current immersive technologies as well as future realities that enhance the experience with features that produce new controllable environments. Overall, these technology-enhanced exergames challenge the adult user and modify the experience by increasing sensory stimulation and creating an environment where virtual and real elements interact. As a therapy, exergames can potentially create new environments and visualizations that may be more ecologically valid and thus simulate real activities of daily living that can be trained. Furthermore, by adding telemedicine features to the exergame, progress over time can be closely monitored and feedback provided, offering future opportunities for cognitive-motor assessment. To more optimally serve and challenge adults both physically and cognitively over time in future lockdowns, there is a need to provide long-term remote training and feedback. Particularly related to activities of daily living that create opportunities for effective and lasting rehabilitation for elderly and sufferers from chronic non-communicable diseases. The aim of the current review is to envision the remote training and monitoring of physical and cognitive aspects for adults with limited mobility, through the implementation of concurrent telehealth and exergame features using XR and wireless sensor technologies. (shrink)

Study of the European Enlightenment could do with a fillip. Perhaps the best tonic we have is combining the close reading of significant works with the study of print history and reader reception....